Transplanted fetal cardiomyocytes as cardiac pacemaker
نویسندگان
چکیده
منابع مشابه
Electrophysiological coupling of transplanted cardiomyocytes.
The recent advances in stem cell biology and tissue engineering have paved the way to the development of a new field in biomedicine, regenerative medicine. This approach seeks to circumvent the shortage of organs for transplantation, by combining the above-mentioned technologies in an attempt to replace diseased or absent tissue. The heart represents an attractive candidate for these emerging t...
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Important questions exist about the relative roles of changes in heart rate versus extent of myocardial shortening in regulating fetal cardiac output, because increases in heart rate created by left atrial pacing have been shown to increase right ventricular output and decrease left ventricular output. Since the pacemaker site could importantly influence foramen ovale flow and, hence, each vent...
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Erosive dermatitis is a skin reaction associated with implantable cardiac devices (ie, pacemakers and cardioverter defibrillators). We report a 65-year-old man with a history of several cerebrovascular attacks who developed an erythematous crusted erosive patch over the pacemaker site after implantation of two subsequent pacemakers. We suggest that physical irritation may be a trigger factor fo...
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A 62-year-old housewife was seen in May 1967 with attacks of dizziness and loss of consciousness. A diagnosis of complete heart block with Stokes-Adams syncope was made. Anterolateral thoracotomy was performed and myocardial electrodes were inserted over the left ventricle and were connected to a Devices fixed-rate pacemaker, inserted in the rectus sheath posterior to the rectus muscle. Postope...
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Pieces of cardiac ventricuhu tissue of late embryonic or l-day postnatal rats, implanted beneath the kidney capsule of adult syngeneic hosts, formed viable, beating transplants. These transplants were investigated over a 40-day postoperative course. In the transplants, cellular binucleation and nuclear polyploidization occurred according to the same schedule as in the heart in situ. The composi...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2002
ISSN: 1010-7940
DOI: 10.1016/s1010-7940(02)00066-0